By extension, Donald Trump lost big, too, because he had enthusiastically endorsed Moore and campaigned for him in the final two weeks of the campaign.
Moore is one of the most odious individuals to run for public office in recent decades. He's stridently theocratic, a blatant LGBT hater, a nasty racist, and an abusive misogynist. He would be happy if America was like a conservative Christian version of Iran. Good riddance to him.
This was a great day for America. The GOP Senate margin is now one seat smaller, bringing it to a razor-thin 51-49 advantage. Best of all, this result was a wakeup call to Republican politicians -- supporting Trump in 2017 and 2018 comes with different consequences than it did in 2016.
Republican Trump won Alabama by a 28 point margin in November 2016. Republican Moore lost Alabama by a 1 point margin in December 2017. That is a historic 29-point shift in a little more than a year.
Moore is now toast. And Trump's defeat in 2020 just got a whole lot closer.